Strength training in addition to neuromuscular exercise and education in individuals with knee osteoarthritis – the effects on pain and sensitization

Review written by Todd Hargrove info

Key Points

  1. It is common for people with knee osteoarthritis to have knee pain as well as widespread hyperalgesia.
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Knee osteoarthritis (KOA) can cause knee pain, and often generalized widespread pain sensitivity. High quality evidence suggests that exercise has hypoalgesic effects in the short and long-term for KOA. But there is a lack of evidence concerning how different methods of exercise affect pain sensitization and pain intensity.

This study examined the effects of neuromuscular exercise and education, with and without additional strength training, on pain intensity and pain sensitization in patients with KOA.

Exercise has hypoalgesic effects in the short and long-term for knee osteoarthritis.
The addition of strength training to neuromuscular exercise and education improved some measures of pain sensitivity.


The study recruited 90 people with KOA. They were randomized into two groups: (1) neuromuscular exercise and education; and (2) neuromuscular exercise, education, and strength training. Each group exercised twice weekly for 12 weeks.

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