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- Associations between sum scores or combinations…
Associations between sum scores or combinations of MRI findings in the lumbar spine and low back pain-related outcomes: a systematic review
Key Points
- Shifting focus to sum scores of MRI findings rather than isolating individual findings could offer a more comprehensive understanding of the underlying mechanisms of low back pain (LBP).
BACKGROUND AND OBJECTIVE
Within the context of low back pain, imaging is often used to assess the biological components. Magnetic resonance imaging (MRI) is widely used and commonly accepted in the clinical assessment of patients with low back pain as it can visualise the anatomical details in the lumbar spine.
This Danish study is the first systematic review to consider the cumulative effect of multiple MRI findings in the aetiology of low back pain (LBP) and its related outcomes. It aimed to explore the relevance of combining all MRI findings on a scan, rather than the traditional tendency of looking at individual findings as contributary mechanisms of LBP. The review offered a foundational change in perspective for future research, suggesting a more standardized approach to the assessment of multiple MRI findings and their clinical relevance.
Multiple degenerative changes within the spine may place a higher structural burden on the spine and that specific MRI findings interact in ways that amplify their clinical impact for the individual.
METHODS
This systematic review (SR) was performed using the PRISMA protocol. Eligible papers included population-based, clinical or mixed samples, with at least 25 participants who had undergone an MRI of the lumbar spine. The studies provided information on associations between any