Efficacy of manual therapy on central sensitization in subjects with chronic low back pain: a systematic review and meta-analysis

Review written by Dr Sarah Haag info

Key Points

  1. Manual therapy/joint mobilizations did not have a significant impact on central sensitization.
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BACKGROUND AND OBJECTIVE

Low back pain continues to be responsible for the most years lived with disability (1) and has an economic burden upwards of $3 billion per year (2,3). Many guidelines for chronic low back pain include the use of manual therapy (4,5), but the impact of manual therapy on the central sensitivity (CS), which is often part of the persistent low back pain presentation, is not currently known.

Therefore, the purpose of the systematic review and meta-analysis was to study the impact of spinal joint manual therapy on CS in individuals with CLBP.

Many guidelines for chronic low back pain include the use of manual therapy but the impact of manual therapy on central sensitivity is not currently known.
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If a person’s presentation is more influenced by central sensitization, manual therapy may not have the desired impact, especially as a stand-alone treatment.

METHODS

  • Eight databases, in addition to clinicaltrials.gov and ICTRP, which include gray literature, were searched for articles published between 2000 and January 2023.
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