- Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce pain through controlling inflammation, but may also negatively impact tissue healing after injury or surgery.
BACKGROUND & OBJECTIVE
Nonsteroidal anti-inflammatory drugs (NSAIDs) are often used to treat pain caused by injury or surgery. Their use is becoming even more common now that opioid use is being discouraged. This study sought to review the effects of short-term NSAID use on soft-tissue healing.
Clinicians should advise patients that their choice of NSAID may impact tissue healing after injury or surgery.
The authors performed a scoping review of all studies examining the effects of NSAIDs on the healing of soft tissues (including ligament, tendon, labrum, and meniscus). Subgroup analyses were done on the basis of the type of NSAID (COX-2 selective